DETA-NONOate

Modify Date: 2024-01-02 15:27:17

DETA-NONOate Structure
DETA-NONOate structure
Common Name DETA-NONOate
CAS Number 146724-94-9 Molecular Weight 163.178
Density 1.5±0.1 g/cm3 Boiling Point 303.0±52.0 °C at 760 mmHg
Molecular Formula C4H13N5O2 Melting Point 98-106ºC
MSDS USA Flash Point 137.1±30.7 °C

 Use of DETA-NONOate


NOC 18 is a nitric oxide donor and activates an inward current in cultured rat cerebellar granules cells. NOC 18 increases cGMP production in cultured vascular smooth muscle cells. NOC 18 reduces contractility of cardiac muscle preparations in vitro.

 Names

Name 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane
Synonym More Synonyms

 DETA-NONOate Biological Activity

Description NOC 18 is a nitric oxide donor and activates an inward current in cultured rat cerebellar granules cells. NOC 18 increases cGMP production in cultured vascular smooth muscle cells. NOC 18 reduces contractility of cardiac muscle preparations in vitro.
Related Catalog

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 303.0±52.0 °C at 760 mmHg
Melting Point 98-106ºC
Molecular Formula C4H13N5O2
Molecular Weight 163.178
Flash Point 137.1±30.7 °C
Exact Mass 163.106918
PSA 108.18000
LogP -1.65
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.588
Storage condition −20°C
Water Solubility H2O: >20 mg/mL

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS KH2502500
HS Code 2928000090

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles57

More Articles
In vivo imaging of reactive oxygen species in mouse brain by using [3H]hydromethidine as a potential radical trapping radiotracer.

J. Cereb. Blood Flow Metab. 34(12) , 1907-13, (2014)

To assess reactive oxygen species (ROS) production by detecting the fluorescent oxidation product, hydroethidine has been used extensively. The present study was undertaken to evaluate the potential o...

Regulation of microglial migration, phagocytosis, and neurite outgrowth by HO-1/CO signaling.

Dev. Neurobiol. 75 , 854-76, (2015)

Clearance of infected and apoptotic neuronal corpses during inflammatory conditions is a fundamental process to create a favorable environment for neuronal recovery. Microglia are the resident immune ...

Preservation of nitric oxide-induced relaxation of porcine coronary artery: roles of the dimers of soluble guanylyl cyclase, phosphodiesterase type 5, and cGMP-dependent protein kinase.

Pflugers Arch. 466(10) , 1999-2008, (2014)

Soluble guanylyl cyclase (sGC), phosphodiesterase type 5 (PDE5), and guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase (PKG) are all dimeric. The present study was to determine the ...

 Synonyms

1,1-Bis(2-aminoethyl)-2-hydroxy-3-oxotriazane
3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene
N-[bis(2-aminoethyl)amino]-N-hydroxynitrous amide
MFCD00278808
Diethylenetriamine nitric oxide adduct
DETA NONOate
2,2'-(hydroxynitrosohydrazono)bis-ethanamine
Ethanamine, 2,2'-(2-hydroxy-3-oxotriazanylidene)bis-