Thrombospondin-1 (1016-1023) (human, bovine, mouse)

Modify Date: 2024-01-21 11:52:23

Thrombospondin-1 (1016-1023) (human, bovine, mouse) Structure
Thrombospondin-1 (1016-1023) (human, bovine, mouse) structure
Common Name Thrombospondin-1 (1016-1023) (human, bovine, mouse)
CAS Number 149234-04-8 Molecular Weight 1128.388
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C56H81N13O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thrombospondin-1 (1016-1023) (human, bovine, mouse)


Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1].

 Names

Name N5-(Diaminomethylene)-L-ornithyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl-L-lysine
Synonym More Synonyms

  Biological Activity

Description Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1].
Related Catalog
In Vitro Thrombospondin-1 (1016-1023) (human, bovine, mouse) (4N1K; 100 µg/mL; for 60 min) 处理会导致单核细胞来源的未成熟树突状细胞 (DC) 中的磷脂酰丝氨酸暴露和细胞膜完整性丧失。当肽浓度为 25-200 µg/mL 时,膜联蛋白 V+ 细胞的数量会随着肽浓度的增加而增加。Thrombospondin-1 (1016-1023) (human, bovine, mouse) 可降低 DC 中的线粒体膜电位和片段化 DNA[2]。
References

[1]. Chih-Jian Lih, et al. Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev. 2006 Aug 1;20(15):2082-95.  

[2]. U Johansson, et al. CD47 ligation induces a rapid caspase-independent apoptosis-like cell death in human monocytes and dendritic cells. Scand J Immunol. 2004 Jan;59(1):40-9.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C56H81N13O10S
Molecular Weight 1128.388
Exact Mass 1127.594971
LogP 3.79
Index of Refraction 1.647

 Synonyms

L-Lysine, N5-(diaminomethylene)-L-ornithyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl-
N5-(Diaminomethylene)-L-ornithyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl-L-lysine