Balsalazide disodium
Modify Date: 2024-01-03 09:32:28
Balsalazide disodium structure
|
Common Name | Balsalazide disodium | ||
|---|---|---|---|---|
| CAS Number | 150399-21-6 | Molecular Weight | 437.312 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H17N3Na2O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Balsalazide disodiumBalsalazide sodium hydrate could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway. |
| Name | Balsalazide disodium |
|---|---|
| Synonym | More Synonyms |
| Description | Balsalazide sodium hydrate could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway. |
|---|---|
| Related Catalog | |
| Target |
STAT3 IL-6 |
| In Vivo | At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group[1]. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug[2]. |
| References |
| Molecular Formula | C17H17N3Na2O8 |
|---|---|
| Molecular Weight | 437.312 |
| Exact Mass | 437.081116 |
| PSA | 172.77000 |
| LogP | 0.30320 |
| RIDADR | UN 2222 3 / PGIII |
|---|---|
| HS Code | 2853009090 |
| HS Code | 2853009090 |
|---|
| Balsalazide Disodium Salt Dihydrate |
| Balsalzide Disodium Hydrate |
| 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic Acid Disodium Salt Dihydrate |
| sodium, μ-[5-[(E)-2-[4-[[[2-(carboxy-κO)ethyl]amino]carbonyl]phenyl]diazenyl]-2-hydroxybenzoato(2-)-κO]-, hydrate (1:2) |
| Balsalazide disodium |
| Sodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate hydrate (2:1:2) |
| Benzoic acid, 5-[(E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-, sodium salt, hydrate (1:2:2) |
| Balsalazide (sodium hydrate) |