Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

Modify Date: 2024-01-10 18:33:06

Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH structure	Common Name	Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
	CAS Number	152246-40-7	Molecular Weight	1308.71000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₀H₁₁₇N₂₁O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM.? histone phosphorylation with IC50 of 80 μM[1][2].

Name	myristoyl-arg-lys-arg-thr-leu-arg-arg-leu-oh
Synonym	More Synonyms

Description	N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM.? histone phosphorylation with IC50 of 80 μM[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> TGF-beta/Smad >> PKC
References	[1]. David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15. [2]. C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79.

Description

Related Catalog

Signaling Pathways >> Epigenetics >> PKC

Research Areas >> Cancer

Signaling Pathways >> TGF-beta/Smad >> PKC

References

[1]. David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15.

[2]. C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79.