Dynorphin A (1-8)

Modify Date: 2024-01-16 13:38:14

Dynorphin A (1-8) Structure
Dynorphin A (1-8) structure
Common Name Dynorphin A (1-8)
CAS Number 75790-53-3 Molecular Weight 981.15200
Density 1.38g/cm3 Boiling Point N/A
Molecular Formula C46H72N14O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dynorphin A (1-8)


Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].

 Names

Name Dynorphin A (1-8), porcine,YGGFLRRI
Synonym More Synonyms

 Dynorphin A (1-8) Biological Activity

Description Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].
Related Catalog
References

[1]. Agbas A, Ahmed MS, Millington W, et al. Dynorphin A(1-8) in human placenta: amino acid sequence determined by tandem mass spectrometry. Peptides. 1995;16(4):623-627.

[2]. Ahmed MS, Zhou DH, Cavinato AG, Maulik D. Opioid binding properties of the purified kappa receptor from human placenta. Life Sci. 1989;44(13):861-871.

 Chemical & Physical Properties

Density 1.38g/cm3
Molecular Formula C46H72N14O10
Molecular Weight 981.15200
Exact Mass 980.55600
PSA 411.05000
LogP 3.68290
Index of Refraction 1.637

 Safety Information

WGK Germany 3

 Synonyms

dynorphin A fragment 1-8
DYNORPHIN A (1-8),PORCINE
DYNORPHIN A PORCINE FRAGMENT 1-8
Ph-8p
GFL PEPTIDE STANDARD
dynorphin A (1-8)
H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH
YGGFLRRI
TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE
dynorphin-(1-8)
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