4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid

Modify Date: 2024-01-10 17:35:07

4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Structure
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid structure
Common Name 4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
CAS Number 1537891-69-2 Molecular Weight 257.372
Density 1.3±0.1 g/cm3 Boiling Point 416.1±41.0 °C at 760 mmHg
Molecular Formula C11H15NO2S2 Melting Point N/A
MSDS N/A Flash Point 205.5±27.6 °C

 Use of 4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid


4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 4-Methyl-4-(2-pyridinyldisulfanyl)pentanoic acid
Synonym More Synonyms

  Biological Activity

Description 4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 416.1±41.0 °C at 760 mmHg
Molecular Formula C11H15NO2S2
Molecular Weight 257.372
Flash Point 205.5±27.6 °C
Exact Mass 257.054413
LogP 3.43
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.600

 Synonyms

4-Methyl-4-(2-pyridinyldisulfanyl)pentanoic acid
Pentanoic acid, 4-methyl-4-(2-pyridinyldithio)-
MFCD27935396