![]() 4-Methyl-4-(methyldisulfanyl)pentanoicacid structure
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Common Name | 4-Methyl-4-(methyldisulfanyl)pentanoicacid | ||
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CAS Number | 796073-55-7 | Molecular Weight | 194.31500 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C7H14O2S2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of 4-Methyl-4-(methyldisulfanyl)pentanoicacid4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Name | 4-methyl-4-(methyldisulfanyl)pentanoic acid |
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Synonym | More Synonyms |
Description | 4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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Related Catalog | |
Target |
Cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
References |
Molecular Formula | C7H14O2S2 |
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Molecular Weight | 194.31500 |
Exact Mass | 194.04400 |
PSA | 87.90000 |
LogP | 2.64100 |
~82% 4-Methyl-4-(met... CAS#:796073-55-7 |
Literature: Zhao, Robert Yongxin; Erickson, Hans K.; Leece, Barbara A.; Reid, Emily E.; Goldmacher, Victor S.; Lambert, John M.; Chari, Ravi V. J. Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 766 - 782 |
~% 4-Methyl-4-(met... CAS#:796073-55-7 |
Literature: Widdison, Wayne C.; Wilhelm, Sharon D.; Cavanagh, Emily E.; Whiteman, Kathleen R.; Leece, Barbara A.; Kovtun, Yelena; Goldmacher, Victor S.; Xie, Hongsheng; Steeves, Rita M.; Lutz, Robert J.; Zhao, Robert; Wang, Lintao; Blaettler, Walter A.; Chari, Ravi V. J. Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4392 - 4408 |
Precursor 2 | |
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DownStream 0 |
4-methyl-4-(methyldithio)pentanoic acid |
Pentanoic acid,4-methyl-4-(methyldithio) |
4-methyl-4-methyldisulfanylpentanoic acid |
4-methyldithio-4-methyl-pentanoic acid |