Olmesartan impurity

Modify Date: 2024-01-10 05:57:00

Olmesartan impurity structure	Common Name	Olmesartan impurity
	CAS Number	154709-18-9	Molecular Weight	494.58600
	Density	1.17g/cm3	Boiling Point	724.8ºC at 760 mmHg
	Molecular Formula	C₃₃H₂₆N₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	392.1ºC

Use of Olmesartan impurity

Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study[1][2].

Name	[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methanol

Description	Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Metabolic Disease
References	[1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7. [2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

Description

Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study[1][2].

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor

Research Areas >> Metabolic Disease

References

[1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.

[2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

Density	1.17g/cm3
Boiling Point	724.8ºC at 760 mmHg
Molecular Formula	C₃₃H₂₆N₄O
Molecular Weight	494.58600
Flash Point	392.1ºC
Exact Mass	494.21100
PSA	63.83000
LogP	6.33960
Vapour Pressure	4.74E-22mmHg at 25°C
Index of Refraction	1.654

5-(2-(4'-(aceto...

CAS#:154709-17-8

~83%

Olmesartan impurity

CAS#:154709-18-9

Literature: Istituto Luso Farmaco D'Italia S.p.A. Patent: US5587390 A1, 1996 ;

5-(4'-(Bromomet...

CAS#:124750-51-2

Olmesartan impurity

CAS#:154709-18-9

Literature: Journal of Medicinal Chemistry, , vol. 35, # 22 p. 4027 - 4038

Precursor 1
CAS#:124750-51-2 5-(4'-(Bromomet...
DownStream 0

Olmesartan impurity

Use of Olmesartan impurity

Names

Olmesartan impurity Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream