154709-18-9

154709-18-9 structure

Name: Olmesartan impurity
Chemical Name: [4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methanol
CAS Number: 154709-18-9
Molecular Formula: C₃₃H₂₆N₄O
Molecular Weight: 494.58600
Catalog: Signaling Pathways GPCR/G Protein Angiotensin Receptor
Create Date: 2016-07-18 11:09:39
Modify Date: 2024-01-10 05:57:00
Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study[1][2].

Name	[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methanol

Description	Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Metabolic Disease
References	[1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7. [2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

154709-17-8

~83%

154709-18-9

Literature: Istituto Luso Farmaco D'Italia S.p.A. Patent: US5587390 A1, 1996 ;

124750-51-2

154709-18-9

Literature: Journal of Medicinal Chemistry, , vol. 35, # 22 p. 4027 - 4038

Precursor 1
124750-51-2
DownStream 0