4-Hydroxyphenylpyruvic acid

Modify Date: 2024-01-03 11:30:24

4-Hydroxyphenylpyruvic acid structure	Common Name	4-Hydroxyphenylpyruvic acid
	CAS Number	156-39-8	Molecular Weight	180.15700
	Density	1.397 g/cm3	Boiling Point	380.8ºC at 760 mmHg
	Molecular Formula	C₉H₈O₄	Melting Point	219-220 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	198.3ºC
	Symbol	GHS07	Signal Word	Warning

Use of 4-Hydroxyphenylpyruvic acid

4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine.

Name	(4-hydroxyphenyl)pyruvic acid
Synonym	More Synonyms

Description	4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine.
Related Catalog	Natural Products >> Others Research Areas >> Others
Target	Human Endogenous Metabolite
References	[1]. Brand LM, et al. Effect of glucagon on phenylalanine metabolism and phenylalanine-degrading enzymes in the rat. Biochem J. 1974 Aug;142(2):231-45.

Density	1.397 g/cm3
Boiling Point	380.8ºC at 760 mmHg
Melting Point	219-220 °C (dec.)(lit.)
Molecular Formula	C₉H₈O₄
Molecular Weight	180.15700
Flash Point	198.3ºC
Exact Mass	180.04200
PSA	74.60000
LogP	0.58840
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.705
Storage condition	2-8°C
Water Solubility	slightly soluble

4-Hydroxyphenylpyruvic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UZ1000000

CHEMICAL NAME :: Pyruvic acid, p-hydroxyphenyl-

CAS REGISTRY NUMBER :: 156-39-8

BEILSTEIN REFERENCE NO. :: 2691632

LAST UPDATED :: 199803

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H8-O4

MOLECULAR WEIGHT :: 180.17

WISWESSER LINE NOTATION :: QVV1R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 gm/kg/10D-C

TOXIC EFFECTS :: Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)

REFERENCE :: JONUAI Journal of Nutrition. (Subscription Dept., 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1928- Volume(issue)/page/year: 95,535,1968

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 gm/kg/10D-C

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)

REFERENCE :: JONUAI Journal of Nutrition. (Subscription Dept., 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1928- Volume(issue)/page/year: 95,535,1968 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 22(6),47,1976

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UZ1000000
HS Code	2918990090

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HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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MFCD00002591

EINECS 205-852-9

3-(4-hydroxyphenyl)-2-oxopropanoic acid

4-Hydroxyphenylpyruvic acid

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China
Product Name: 4-Hydroxyphenylpyruvic acid
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Dayang Chem (Hangzhou) Co., Ltd.
China
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4-Hydroxyphenylpyruvic acid
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Purity: 99.0%
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4-Hydroxyphenylpyruvic acid

Use of 4-Hydroxyphenylpyruvic acid

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