1-Methyladenosine

Modify Date: 2024-01-05 10:56:26

1-Methyladenosine Structure
1-Methyladenosine structure
 Common Name 1-Methyladenosine
CAS Number 15763-06-1 Molecular Weight 281.268
Density 1.9±0.1 g/cm3 Boiling Point 655.4±65.0 °C at 760 mmHg
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point 350.2±34.3 °C

 Use of 1-Methyladenosine


1-Methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.

 Names

Name 1-methyladenosine
Synonym More Synonyms

 1-Methyladenosine Biological Activity

Description 1-Methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Hauenschild R, et al. The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent. Nucleic Acids Res. 2015 Nov 16;43(20):9950-64.

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 655.4±65.0 °C at 760 mmHg
Molecular Formula C11H15N5O4
Molecular Weight 281.268
Flash Point 350.2±34.3 °C
Exact Mass 281.112396
PSA 129.41000
LogP -3.27
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.824
Storage condition 2-8℃

 Synthetic Route

Trimethylsulfonium iodide structure

Trimethylsulfon...

CAS#:2181-42-2

Adenosine structure

Adenosine

CAS#:58-61-7

~68%

1-Methyladenosine Structure

1-Methyladenosine

CAS#:15763-06-1

Literature: Yamauchi, Kiyoshi; Nakagima, Toru; Kinoshita, Masayoshi Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2787 - 2792
Trimethylsulfonium hydroxide structure

Trimethylsulfon...

CAS#:17287-03-5

Adenosine structure

Adenosine

CAS#:58-61-7

~4%

N6,O3'-methyladenosine structure

N6,O3'-methylad...

CAS#:60037-52-7

N6,2′-O-Dimethyladenosine structure

N6,2′-O-Dimethy...

CAS#:57817-83-1

Detail
Literature: Yamauchi, Kiyoshi; Nakagima, Toru; Kinoshita, Masayoshi Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2787 - 2792
trimethylselenonium hydroxyde structure

trimethylseleno...

CAS#:74230-06-1

Adenosine structure

Adenosine

CAS#:58-61-7

~6%

N6,2′-O-Dimethyladenosine structure

N6,2′-O-Dimethy...

CAS#:57817-83-1

2'-O-Methyladenosine structure

2'-O-Methyladenosine

CAS#:2140-79-6

Detail
Literature: Yamauchi, Kiyoshi; Hattori, Kazue; Kinoshita, Masayoshi Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1327 - 1330
Dimethyl sulfate structure

Dimethyl sulfate

CAS#:77-78-1

Adenosine structure

Adenosine

CAS#:58-61-7

~%

1-Methyladenosine Structure

1-Methyladenosine

CAS#:15763-06-1

Literature: Bredereck et al. Chemische Berichte, 1948 , vol. 81, p. 307,312 Full Text Show Details Wacker; Ebert Zeitschrift fuer Naturforschung, 1959 , vol. 14b, p. 709,711

 Synonyms

1-Methyladenosine
Adenosine, N,6-didehydro-1,6-dihydro-1-methyl-
N,6-DIDEHYDRO-1,6-DIHYDRO-1-METHYLADENOSINE
Adenosine, 1-methyl-
1-methyl-6,N6-didehydro-1,6-dihydro-adenosine
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