2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine

Modify Date: 2024-01-06 22:39:03

2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine Structure
2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine structure
Common Name 2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine
CAS Number 158665-47-5 Molecular Weight 559.61
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C31H33N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine


2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-Amino-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine
Synonym More Synonyms

  Biological Activity

Description 2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C31H33N3O7
Molecular Weight 559.61
Exact Mass 559.231873
LogP 4.80
Index of Refraction 1.607

 Synonyms

Thymidine, 2'-amino-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-
2'-Amino-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine