2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine

Modify Date: 2024-01-02 16:57:43

2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine Structure
2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine structure
Common Name 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine
CAS Number 161696-76-0 Molecular Weight 298.41
Density 1.38g/cm3 Boiling Point 489.2ºC at 760 mmHg
Molecular Formula C16H18N4S Melting Point 144.5ºC
MSDS N/A Flash Point 249.7ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine


N-Desmethylolanzapine is an antipsychotic drug.The formation of N-Desmethylolanzapine correlates with the level and activityof human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapinecan be used in the study of antipsychotic drugs [1].

 Names

Name N-Demethyl Olanzapine
Synonym More Synonyms

  Biological Activity

Description N-Desmethylolanzapine is an antipsychotic drug.The formation of N-Desmethylolanzapine correlates with the level and activityof human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapinecan be used in the study of antipsychotic drugs [1].
Related Catalog
References

[1]. Ring BJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther. 1996 Feb;276(2):658-66.  

 Chemical & Physical Properties

Density 1.38g/cm3
Boiling Point 489.2ºC at 760 mmHg
Melting Point 144.5ºC
Molecular Formula C16H18N4S
Molecular Weight 298.41
Flash Point 249.7ºC
Exact Mass 298.12500
PSA 67.90000
LogP 2.93730
Vapour Pressure 1.02E-09mmHg at 25°C
Index of Refraction 1.742
Storage condition -20°C Freezer

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302-H319
Precautionary Statements P210-P305 + P351 + P338
Hazard Codes F,Xn
Risk Phrases 11-20/21/22-36
Safety Phrases 16-26-36/37
RIDADR UN 1648 3 / PGII
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Desmethylolanzapine dihydrochloride
2-methyl-4-piperazin-1-yl-5H-thieno[3,2-c][1,5]benzodiazepine
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