P2X7 receptor antagonist-3

Modify Date: 2024-01-16 22:35:55

P2X7 receptor antagonist-3 structure	Common Name	P2X7 receptor antagonist-3
	CAS Number	1627900-92-8	Molecular Weight	408.76
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₂ClF₃N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of P2X7 receptor antagonist-3

P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats[1].

Name	P2X7 receptor antagonist-3

Description	P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor Research Areas >> Neurological Disease
Target	hP2X7R:4.2 nM (IC50) rP2X7R:6.8 nM (IC50)
References	[1]. Brad M Savall, et al. Synthesis, SAR, and Pharmacological Characterization of Brain Penetrant P2X7 Receptor Antagonists. ACS Med Chem Lett. 2015 Apr 24;6(6):671-6.

Molecular Formula	C₁₇H₁₂ClF₃N₆O
Molecular Weight	408.76