cGAS inhibitor 467

Modify Date: 2024-01-08 16:18:44

cGAS inhibitor 467 Structure
cGAS inhibitor 467 structure
Common Name cGAS inhibitor 467
CAS Number 1628332-52-4 Molecular Weight 319.32
Density N/A Boiling Point N/A
Molecular Formula C17H13N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of cGAS inhibitor 467


GSK467 is a selective KDM5 (JARID1) inhibitor with a Ki of 10 nM for KDM5B, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members[1].

 Names

Name GSK467

 cGAS inhibitor 467 Biological Activity

Description GSK467 is a selective KDM5 (JARID1) inhibitor with a Ki of 10 nM for KDM5B, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members[1].
Related Catalog
Target

Ki: 10 nM (KDM5B)[1]

References

[1]. Johansson C, et al. Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat Chem Biol. 2016 Jul;12(7):539-45.

 Chemical & Physical Properties

Molecular Formula C17H13N5O2
Molecular Weight 319.32
Storage condition 2-8℃
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Price: ¥2420/10 mM * 1 mL in DMSO

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