SSTR5 antagonists 1

Modify Date: 2024-01-09 11:09:50

SSTR5 antagonists 1 Structure
SSTR5 antagonists 1 structure
 Common Name SSTR5 antagonists 1
CAS Number 1628741-91-2 Molecular Weight 511.59
Density N/A Boiling Point N/A
Molecular Formula C28H34FN3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SSTR5 antagonists 1


SSTR5 antagonists 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]

 Names

Name SSTR5 antagonists 1

 SSTR5 antagonists 1 Biological Activity

Description SSTR5 antagonists 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]
Related Catalog
Target

IC50: 9.6 nM (hSSTR5), 57 nM (mSSTR5)[1]

References

[1]. Hirose H, et al. Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus. Bioorg Med Chem. 2017 Aug 1;25(15):4175-4193.

 Chemical & Physical Properties

Molecular Formula C28H34FN3O5
Molecular Weight 511.59
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