Rezafungin acetate

Modify Date: 2024-01-13 15:04:45

Rezafungin acetate Structure
Rezafungin acetate structure
Common Name Rezafungin acetate
CAS Number 1631754-41-0 Molecular Weight 1285.44
Density N/A Boiling Point N/A
Molecular Formula C65H88N8O19 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Rezafungin acetate


Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].

 Names

Name Rezafungin acetate

 Rezafungin acetate Biological Activity

Description Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].
Related Catalog
In Vivo Rezafungin acetate (Biafungin acetate) (1 mg/kg; i.p. once daily for 6 days) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model[1]. Animal Model: C3H/HeN mice[1] Dosage: 1 mg/kg Administration: Intraperitoneal injection; once daily for 6 days Result: Significantly reduced nuclei and asci burdens.
References

[1]. Melanie Cushion, et al. Rezafungin Prophylactic Efficacy in a Mouse Model of Pneumocystis Pneumonia. VOLUME 25, ISSUE 3, SUPPLEMENT, S366, MARCH 01, 2019.

[2]. Sofjan AK, et al. Rezafungin (CD101), a next-generation echinocandin: A systematic literature review and assessment of possible place in therapy. J Glob Antimicrob Resist. 2018 Sep;14:58-64.

 Chemical & Physical Properties

Molecular Formula C65H88N8O19
Molecular Weight 1285.44
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