Pristane-d40

Modify Date: 2024-01-02 18:36:07

Pristane-d40 Structure
Pristane-d40 structure
Common Name Pristane-d40
CAS Number 16416-35-6 Molecular Weight 308.76700
Density N/A Boiling Point N/A
Molecular Formula C19D40 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pristane-d40


Pristane-d40 is the deuterium labeled Pristane[1]. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[2]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[3].

 Names

Name 2,6,10,14-tetramethylpentadecane-d40
Synonym More Synonyms

 Pristane-d40 Biological Activity

Description Pristane-d40 is the deuterium labeled Pristane[1]. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[2]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. J J Turner, et al. Krypton Fluoride: Preparation by the Matrix Isolation Technique. Science. 1963 May 31;140(3570):974-5.  

[3]. Jens Holmberg,et al. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J Immunol. 2006 Jan 15176(2):1172-9.  

 Chemical & Physical Properties

Molecular Formula C19D40
Molecular Weight 308.76700
Exact Mass 308.56400
LogP 7.08150

 Synonyms

Pristan-1-ol
1-Pentadecanol,2,6,10,14-tetramethyl
norphytanol
Pristan-d40
2H,6H,10H,14H-octacosadeuterio-2,6,10,14-tetrakis-trideuteriomethyl-pentadecane
2,6,10,14-tetramethyl-pentadecan-1-ol