(Rac)-Tavapadon
Modify Date: 2024-01-10 21:44:56
(Rac)-Tavapadon structure
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Common Name | (Rac)-Tavapadon | ||
|---|---|---|---|---|
| CAS Number | 1643462-64-9 | Molecular Weight | 391.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H16F3N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (Rac)-Tavapadon(Rac)-Tavapadon ((Rac)-PF-06649751; (Rac)-CVL-751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC50=0.8 nM; β-arrestin2, EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity[1]. |
| Name | (Rac)-Tavapadon |
|---|
| Description | (Rac)-Tavapadon ((Rac)-PF-06649751; (Rac)-CVL-751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC50=0.8 nM; β-arrestin2, EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity[1]. |
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| Related Catalog | |
| Target |
D1 Receptor |
| In Vitro | (Rac)-Tavapadon ((Rac)-PF-06649751; (Rac)-CVL-751; compound 32) has EMAXs of 118% and 30% in the GS activation assay and the β-arrestin2 recruitment assay[1]. |
| References |
| Molecular Formula | C19H16F3N3O3 |
|---|---|
| Molecular Weight | 391.34 |