4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine

Modify Date: 2024-02-01 20:30:02

4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine Structure
4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine structure
Common Name 4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
CAS Number 169516-61-4 Molecular Weight 268.24
Density 1.8±0.1 g/cm3 Boiling Point 603.1±55.0 °C at 760 mmHg
Molecular Formula C11H13FN4O3 Melting Point N/A
MSDS N/A Flash Point 318.5±31.5 °C

 Use of 4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine


2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 7-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Synonym More Synonyms

  Biological Activity

Description 2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 603.1±55.0 °C at 760 mmHg
Molecular Formula C11H13FN4O3
Molecular Weight 268.24
Flash Point 318.5±31.5 °C
Exact Mass 268.097168
LogP -0.22
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.774

 Synonyms

MFCD25542480
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
7-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine