PEG4-sulfonic acid

Modify Date: 2024-01-09 21:23:17

PEG4-sulfonic acid Structure
PEG4-sulfonic acid structure
Common Name PEG4-sulfonic acid
CAS Number 173459-90-0 Molecular Weight 258.289
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C8H18O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PEG4-sulfonic acid


PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Hydroxy-PEG3-sulfonic acid
Synonym More Synonyms

 PEG4-sulfonic acid Biological Activity

Description PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C8H18O7S
Molecular Weight 258.289
Exact Mass 258.077332
LogP -3.31
Index of Refraction 1.486

 Synonyms

Ethanesulfonic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-
2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}ethanesulfonic acid
MFCD29042364
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