AN2718
Modify Date: 2024-01-10 12:37:41
AN2718 structure
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Common Name | AN2718 | ||
|---|---|---|---|---|
| CAS Number | 174672-06-1 | Molecular Weight | 168.38500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H6BClO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AN2718AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism. |
| Name | 5-chloro-1-hydroxy-3H-2,1-benzoxaborole |
|---|---|
| Synonym | More Synonyms |
| Description | AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism. |
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| Related Catalog | |
| Target |
Fungal[1]. |
| In Vitro | AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus, and from yeasts, C. albicans, with an IC50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T.mentagrophytes[1]. |
| References |
| Molecular Formula | C7H6BClO2 |
|---|---|
| Molecular Weight | 168.38500 |
| Exact Mass | 168.01500 |
| PSA | 29.46000 |
| LogP | 0.55770 |
| Storage condition | 2-8℃ |
| 5-chloro-1,3-dihydro-2,1-benzoxaborol-1-ol |
| 2,1-Benzoxaborole,5-chloro-1,3-dihydro-1-hydroxy |
| UNII-810U6C2DGG |
| 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole |
| AN2718 |