Metergoline
Modify Date: 2024-01-08 20:00:30
Metergoline structure
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Common Name | Metergoline | ||
|---|---|---|---|---|
| CAS Number | 17692-51-2 | Molecular Weight | 403.51700 | |
| Density | 1.25g/cm3 | Boiling Point | 612.5ºC at 760mmHg | |
| Molecular Formula | C25H29N3O2 | Melting Point | 148-150 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 324.2ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of MetergolineMetergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. |
| Name | metergoline |
|---|---|
| Synonym | More Synonyms |
| Description | Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. |
|---|---|
| Related Catalog |
| Density | 1.25g/cm3 |
|---|---|
| Boiling Point | 612.5ºC at 760mmHg |
| Melting Point | 148-150 °C(lit.) |
| Molecular Formula | C25H29N3O2 |
| Molecular Weight | 403.51700 |
| Flash Point | 324.2ºC |
| Exact Mass | 403.22600 |
| PSA | 46.50000 |
| LogP | 4.39350 |
| Vapour Pressure | 0mmHg at 25°C |
| Storage condition | −20°C |
| Water Solubility | 0.1 M HCl: 1.4 mg/mL |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 20/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful by inhalation and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be absorbed through the skin in harmful amounts. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a tightly closed container. Store in a dry area. Deep freeze (below -20C). Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 17692-51-2: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: white Odor: odorless pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 148 deg C(decom) Autoignition Temperature: 466 deg C ( 870.80 deg F) Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: 150 deg C Solubility in water: hardly soluble Specific Gravity/Density: 0.560 Molecular Formula: C25H29N3O2 Molecular Weight: 403.53 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, direct sunlight.. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 17692-51-2: FA1070000 LD50/LC50: CAS# 17692-51-2: Oral, mouse: LD50 = 430 mg/kg. Carcinogenicity: Metergoline - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/22 Harmful by inhalation and if swallowed. Safety Phrases: S 7/9 Keep container tightly closed and in a well-ventilated place. S 23 Do not inhale gas/fumes/vapour/spray. WGK (Water Danger/Protection) CAS# 17692-51-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 17692-51-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 17692-51-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22 |
| Safety Phrases | S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | FA1070000 |
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Pharmacological characterisation of the thermogenic effect of bupropion.
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| Metergoline,[(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamicacidphenylmethylester |
| EINECS 241-686-3 |
| MFCD00153829 |