BMS-193884

Modify Date: 2024-02-28 17:24:59

BMS-193884 structure	Common Name	BMS-193884
	CAS Number	176960-47-7	Molecular Weight	395.43200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₇N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BMS-193884

BMS-193884 is a selective, orally active, and competitive ETA antagonist with 10000-fold greater affinity for the human ETA receptor (Ki=1.4 nM) than for the ETB receptor[1].

Name	N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-[4-(1,3-oxazol-2-yl)phenyl]benzenesulfonamide

Description	BMS-193884 is a selective, orally active, and competitive ETA antagonist with 10000-fold greater affinity for the human ETA receptor (Ki=1.4 nM) than for the ETB receptor[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor
Target	ETA:1.4 nM (Ki) ETB:18700 nM (Ki)
References	[1]. Murugesan N, et al. Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally active ET(A) selective antagonist. J Med Chem. 2003;46(1):125-137.

Molecular Formula	C₂₀H₁₇N₃O₄S
Molecular Weight	395.43200
Exact Mass	395.09400
PSA	106.61000
LogP	5.56800

N-(3,4-dimethyl-5-isoxazolyl)-N-[(methoxyethoxy)methyl]-4'-(2-oxazolyl)[1,1'-biphenyl]-2-sulfonamide structure

N-(3,4-dimethyl...

CAS#:176961-14-1

~53%

BMS-193884 Structure

BMS-193884

CAS#:176960-47-7

Literature: Journal of Medicinal Chemistry, , vol. 43, # 16 p. 3111 - 3117

4-Bromobenzoyl chloride structure

4-Bromobenzoyl ...

CAS#:586-75-4

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BMS-193884 Structure

BMS-193884

CAS#:176960-47-7

Literature: Journal of Medicinal Chemistry, , vol. 43, # 16 p. 3111 - 3117

Benzamide, 4-bromo- structure

Benzamide, 4-bromo-

CAS#:698-67-9

~%

BMS-193884 Structure

BMS-193884

CAS#:176960-47-7

Literature: Journal of Medicinal Chemistry, , vol. 43, # 16 p. 3111 - 3117

2-(4-Bromophenyl)-1,3-oxazole structure

2-(4-Bromopheny...

CAS#:176961-50-5

~%

BMS-193884 Structure

BMS-193884

CAS#:176960-47-7

Literature: Journal of Medicinal Chemistry, , vol. 43, # 16 p. 3111 - 3117

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BMS-193884
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: BMS-193884
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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