Maprotiline-d5 hydrochloride

Modify Date: 2024-01-12 16:05:30

Maprotiline-d5 hydrochloride Structure
Maprotiline-d5 hydrochloride structure
Common Name Maprotiline-d5 hydrochloride
CAS Number 1794942-12-3 Molecular Weight 318.90
Density N/A Boiling Point N/A
Molecular Formula C20H19D5ClN Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Maprotiline-d5 hydrochloride


Maprotiline-d5 hydrochloride is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].

 Names

Name Maprotiline-d5 hydrochloride

 Maprotiline-d5 hydrochloride Biological Activity

Description Maprotiline-d5 hydrochloride is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8.

[3]. http://en.wikipedia.org/wiki/Maprotiline

 Chemical & Physical Properties

Molecular Formula C20H19D5ClN
Molecular Weight 318.90

 Safety Information

Hazard Codes Xn