Iopamidol-d8

Modify Date: 2024-01-13 06:42:15

Iopamidol-d8 Structure
Iopamidol-d8 structure
Common Name Iopamidol-d8
CAS Number 1795778-90-3 Molecular Weight 785.13
Density N/A Boiling Point N/A
Molecular Formula C17H14D8I3N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Iopamidol-d8


Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1].

 Names

Name Iopamidol-d8

 Iopamidol-d8 Biological Activity

Description Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Longo DL, et, al. Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T. Magn Reson Med. 2011 Jan;65(1):202-11.

 Chemical & Physical Properties

Molecular Formula C17H14D8I3N3O8
Molecular Weight 785.13