1795778-90-3

1795778-90-3 structure

Name: Iopamidol-d8
Chemical Name: Iopamidol-d8
CAS Number: 1795778-90-3
Molecular Formula: C₁₇H₁₄D₈I₃N₃O₈
Molecular Weight: 785.13
Catalog: Research Areas Others
Create Date: 2021-10-12 09:30:44
Modify Date: 2024-01-13 06:42:15
Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1].

Name	Iopamidol-d8

Description	Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Longo DL, et, al. Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T. Magn Reson Med. 2011 Jan;65(1):202-11.

Molecular Formula	C₁₇H₁₄D₈I₃N₃O₈
Molecular Weight	785.13