QX-77
Modify Date: 2024-01-09 18:33:33
QX-77 structure
|
Common Name | QX-77 | ||
|---|---|---|---|---|
| CAS Number | 1798331-92-6 | Molecular Weight | 300.74 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H13ClN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of QX-77QX77 is a chaperone-mediated autophagy (CMA) activator. |
| Name | QX77 |
|---|
| Description | QX77 is a chaperone-mediated autophagy (CMA) activator. |
|---|---|
| Related Catalog | |
| Target |
CMA[1] |
| In Vitro | Treatment with CMA activator QX77 rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells. QX77 treatment also increases LAMP2A localization at the lysosomal membrane[1]. |
| Cell Assay | Mouse embryo fibroblasts are preincubated with QX77 or vehicle (DMSO) 48 h before the addition of tert-butyl hydroperoxide. After an overnight incubation, cell viability is determined by a modified version of the MTT assay[1]. |
| References |
| Molecular Formula | C16H13ClN2O2 |
|---|---|
| Molecular Weight | 300.74 |
| Storage condition | 2-8℃ |