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China
Product Name: Carcainium chloride
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China
Product Name: Carcainium chloride(QX 572)
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DC Chemicals Limited
China
Product Name: Carcainium chloride
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Carcainium chloride
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1042-42-8

1042-42-8 structure

1042-42-8 structure

Name: QX 572
Chemical Name: bis(2-anilino-2-oxoethyl)-dimethylazanium,chloride
CAS Number: 1042-42-8
Molecular Formula: C₁₈H₂₂ClN₃O₂
Molecular Weight: 347.83900
Catalog: Research Areas Others
Create Date: 2018-04-25 08:00:00
Modify Date: 2024-01-08 11:51:46
Carcainium chloride (QX 572) is a quaternary derivative of the local anesthetic Lidocaine. Antitussive effect[1][2].

Name	bis(2-anilino-2-oxoethyl)-dimethylazanium,chloride
Synonyms	carcainium chloride qx-572

Description	Carcainium chloride (QX 572) is a quaternary derivative of the local anesthetic Lidocaine. Antitussive effect[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Lavorini F, et al. Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study. Pulm Pharmacol Ther. 2016 Oct;40:91-4. [2]. Adcock JJ, et al. RSD931, a novel anti-tussive agent acting on airway sensory nerves. Br J Pharmacol. 2003 Feb;138(3):407-16.

Molecular Formula	C₁₈H₂₂ClN₃O₂
Molecular Weight	347.83900
Exact Mass	347.14000
PSA	58.20000

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH2778000

CHEMICAL NAME :: Ethanaminium, N,N-dimethyl-2-oxo-N-(2-oxo-2-(phenylamino)ethyl)-2-( phenylamino)-, chloride

CAS REGISTRY NUMBER :: 1042-42-8

LAST UPDATED :: 199204

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H22-N3-O2.Cl

MOLECULAR WEIGHT :: 347.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 94 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 50,212,1987