BAY 876

Modify Date: 2024-01-04 20:55:00

BAY 876 Structure
BAY 876 structure
Common Name BAY 876
CAS Number 1799753-84-6 Molecular Weight 496.417
Density 1.5±0.1 g/cm3 Boiling Point 632.3±55.0 °C at 760 mmHg
Molecular Formula C24H16F4N6O2 Melting Point N/A
MSDS N/A Flash Point 336.2±31.5 °C

 Use of BAY 876


BAY-876 is the first highly selective GLUT1 inhibitor with IC50 of 0.002 uM. show good metabolic stability in vitro and high oral bioavailability in vivo.

 Names

Name N4-[1-(4-Cyanobenzyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide
Synonym More Synonyms

 BAY 876 Biological Activity

Description BAY-876 is the first highly selective GLUT1 inhibitor with IC50 of 0.002 uM. show good metabolic stability in vitro and high oral bioavailability in vivo.
Related Catalog
References

[1]. Siebeneicher H et al. Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. ChemMedChem. 2016 Aug 23.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 632.3±55.0 °C at 760 mmHg
Molecular Formula C24H16F4N6O2
Molecular Weight 496.417
Flash Point 336.2±31.5 °C
Exact Mass 496.127075
LogP 3.89
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.649
Storage condition -20℃

 Synonyms

N-[1-(4-Cyanobenzyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide
2,4-Quinolinedicarboxamide, N-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-
BAY-876
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Price: $131/10mM*1mLinDMSO

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