7-Chloro-4-hydroxyquinoline-2-carboxylic acid
Modify Date: 2024-01-10 19:23:35
7-Chloro-4-hydroxyquinoline-2-carboxylic acid structure
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Common Name | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid | ||
|---|---|---|---|---|
| CAS Number | 18000-24-3 | Molecular Weight | 223.61300 | |
| Density | 1.549 g/cm3 | Boiling Point | 395ºC at 760 mmHg | |
| Molecular Formula | C10H6ClNO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 192.7ºC | |
Use of 7-Chloro-4-hydroxyquinoline-2-carboxylic acid7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. |
| Name | 7-chlorokynurenic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. |
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| Related Catalog | |
| Target |
N-methyl-D-aspartate receptor[1] Ki: 0.59 μM (reuptake of glutamate)[1] |
| References |
| Density | 1.549 g/cm3 |
|---|---|
| Boiling Point | 395ºC at 760 mmHg |
| Molecular Formula | C10H6ClNO3 |
| Molecular Weight | 223.61300 |
| Flash Point | 192.7ºC |
| Exact Mass | 223.00400 |
| PSA | 70.42000 |
| LogP | 2.29200 |
| Vapour Pressure | 6E-07mmHg at 25°C |
| Index of Refraction | 1.648 |
| Storage condition | Store at RT |
| Water Solubility | 0.1 M NaOH: 13.7 mg/mL |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S36 |
| WGK Germany | 3 |
| HS Code | 2933499090 |
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7-Chloro-4-hydr... CAS#:18000-24-3 |
| Literature: Journal of the American Chemical Society, , vol. 68, p. 113,115 |
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7-Chloro-4-hydr... CAS#:18000-24-3 |
| Literature: Chemische Berichte, , vol. 81, p. 499,505 Journal of the American Chemical Society, , vol. 68, p. 113,115 |
CAS#:86-99-7
CAS#:86-98-6
CAS#:5347-19-3![2-Propanol,1-[(7-chloro-4-quinolinyl)amino]- 3-(diethylamino)- structure](https://image.chemsrc.com/caspic/159/525-31-5.png)
CAS#:525-31-5| HS Code | 2933499090 |
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| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 7-chloro-4-hydroxyquinoline-2-carboxylic acid |
| 7-chloro-4-oxo-1H-quinoline-2-carboxylic acid |
| 7-Chlorokynurenic acid |
| MFCD00674924 |
| EINECS 241-913-6 |
| 7-chloro-4-hydroxy-2-carboxyquinoline |
| 7-Cl-KYNA |