ITH 12575

Modify Date: 2024-01-12 12:03:21

ITH 12575 Structure
ITH 12575 structure
Common Name ITH 12575
CAS Number 1802013-08-6 Molecular Weight 331.860
Density 1.2±0.1 g/cm3 Boiling Point 484.5±45.0 °C at 760 mmHg
Molecular Formula C18H18ClNOS Melting Point N/A
MSDS N/A Flash Point 246.8±28.7 °C

 Use of ITH 12575


ITH12575, a CGP37157 derivative, is a potent and selective mNCX blocker. ITH12575 reduces Ca2+ influx through CALHM1 at low micromolar concentrations[1][2].

 Names

Name ITH12575
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 484.5±45.0 °C at 760 mmHg
Molecular Formula C18H18ClNOS
Molecular Weight 331.860
Flash Point 246.8±28.7 °C
Exact Mass 331.079773
LogP 5.76
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.604

 Synonyms

7-Chloro-5-(2'-isopropylphenyl)-3,5-dihydro-4,1-benzothiazepin-2-(1H)-one
4,1-Benzothiazepin-2(3H)-one, 7-chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-
7-Chloro-5-(2-isopropylphenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
ITH12575
MFCD30720887