Peiminine

Modify Date: 2024-01-02 11:03:52

Peiminine Structure
Peiminine structure
Common Name Peiminine
CAS Number 18059-10-4 Molecular Weight 429.635
Density 1.2±0.1 g/cm3 Boiling Point 567.1±50.0 °C at 760 mmHg
Molecular Formula C27H43NO3 Melting Point 212-213ºC
MSDS N/A Flash Point 296.8±30.1 °C

 Use of Peiminine


Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.

 Names

Name Peiminine
Synonym More Synonyms

 Peiminine Biological Activity

Description Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.
Related Catalog
References

[1]. Guo H, et al. Peiminine ameliorates bleomycin-induced acute lung injury in rats. Mol Med Rep. 2013 Apr;7(4):1103-10.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 567.1±50.0 °C at 760 mmHg
Melting Point 212-213ºC
Molecular Formula C27H43NO3
Molecular Weight 429.635
Flash Point 296.8±30.1 °C
Exact Mass 429.324280
PSA 60.77000
LogP 3.90
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.585

 Safety Information

Hazard Codes Xi

 Synthetic Route

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Peiminine Structure

Peiminine

CAS#:18059-10-4

Literature: Heterocycles, , vol. 15, # 2 p. 791 - 796

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

MFCD00210542
(3β)-3,20-Dihydroxycevan-6-one
Osnovanine
Raddeamine
(3β,5α)-3,20-Dihydroxycevan-6-one
Cevan-6-one, 3,20-dihydroxy-, (3β,5α)-
Sipeimine
3beta,20-Dihydroxy-5alpha-cevan-6-one
3β,20-Dihydroxy-5α-cevan-6-one
(3b)-3,20-Dihydroxycevan-6-one
RADDEANINE
Cevan-6-one, 3,20-dihydroxy-, (3β)-
cevan-6-one, 3,20-dihydroxy-, (3b)-
PEINININE
Fritillarine
Verticinone
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