Ald-Ph-amido-PEG2-C2-Boc

Modify Date: 2024-02-05 12:21:44

Ald-Ph-amido-PEG2-C2-Boc Structure
Ald-Ph-amido-PEG2-C2-Boc structure
Common Name Ald-Ph-amido-PEG2-C2-Boc
CAS Number 1807521-09-0 Molecular Weight 365.421
Density 1.1±0.1 g/cm3 Boiling Point 547.6±45.0 °C at 760 mmHg
Molecular Formula C19H27NO6 Melting Point N/A
MSDS N/A Flash Point 285.0±28.7 °C

 Use of Ald-Ph-amido-PEG2-C2-Boc


Ald-Ph-amido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ald-Ph-PEG2-t-butyl ester
Synonym More Synonyms

 Ald-Ph-amido-PEG2-C2-Boc Biological Activity

Description Ald-Ph-amido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 547.6±45.0 °C at 760 mmHg
Molecular Formula C19H27NO6
Molecular Weight 365.421
Flash Point 285.0±28.7 °C
Exact Mass 365.183838
LogP 1.86
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.520

 Synonyms

ALD-PH-PEG2-CH2CH2COOTBU
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