Proflavine (hemisulfate)

Modify Date: 2024-01-02 15:38:27

Proflavine (hemisulfate) Structure
Proflavine (hemisulfate) structure
Common Name Proflavine (hemisulfate)
CAS Number 1811-28-5 Molecular Weight 258.29
Density 1.346 g/cm3 Boiling Point 506.9ºC at 760 mmHg
Molecular Formula C13H11N3.1/2H2O4S Melting Point 284-286ºC
MSDS Chinese USA Flash Point 292.9ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Proflavine (hemisulfate)


Proflavine hemisulfate is an Acridine derivative, which is a slow-acting disinfectant with bacteriostatic action against many Gram-positive bacteria but less effective against Gram-negative organisms.

 Names

Name proflavine hemisulfate
Synonym More Synonyms

 Proflavine (hemisulfate) Biological Activity

Description Proflavine hemisulfate is an Acridine derivative, which is a slow-acting disinfectant with bacteriostatic action against many Gram-positive bacteria but less effective against Gram-negative organisms.
Related Catalog

 Chemical & Physical Properties

Density 1.346 g/cm3
Boiling Point 506.9ºC at 760 mmHg
Melting Point 284-286ºC
Molecular Formula C13H11N3.1/2H2O4S
Molecular Weight 258.29
Flash Point 292.9ºC
PSA 64.93000
LogP 3.71480
Vapour Pressure 0mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR9065100
CAS REGISTRY NUMBER :
1811-28-5
LAST UPDATED :
199701
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C13-H11-N3.1/2H2-O4-S
MOLECULAR WEIGHT :
258.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
15 umol/L
REFERENCE :
JMOBAK Journal of Molecular Biology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 13,138,1965 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AR9065100
HS Code 2933990090

 Synthetic Route

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Proflavine (hemisulfate) Structure

Proflavine (hem...

CAS#:1811-28-5

Literature: Chemische Berichte, , vol. 46, p. 1941

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00149650
PROFLAVINE HEMISULPHATE
proflavine sulphate
PROFLAVINE SULFATE
3,6-Diaminoacridinium Monohydrogen Sulfate Hydrate
proflavin hemisulfate
Proflavine hemisulfate salt hydrate
Proflavine Hemisulfate
2 8-DIAMINOACRIDINE SULFATE
EINECS 217-320-3
3,6-DIAMINOACRIDINE HEMISULFATE
Proflavine HeMisulfate Hydrate
3,6-Acridinediamine,sulfate,2:1)
Proflavine (hemisulfate)
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