Azide-PEG12-Tos

Modify Date: 2024-01-02 15:41:47

Azide-PEG12-Tos Structure
Azide-PEG12-Tos structure
Common Name Azide-PEG12-Tos
CAS Number 1821464-56-5 Molecular Weight 725.85
Density N/A Boiling Point N/A
Molecular Formula C31H55N3O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azide-PEG12-Tos


Azide-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azide-PEG12-Tos

 Azide-PEG12-Tos Biological Activity

Description Azide-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C31H55N3O14S
Molecular Weight 725.85
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