EGFR-IN-87

Modify Date: 2024-01-29 17:20:14

EGFR-IN-87 structure	Common Name	EGFR-IN-87
	CAS Number	1835666-87-9	Molecular Weight	499.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₃N₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-87

EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research[1].

Name	EGFR-IN-87

Description	EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR tyrosine kinase inhibitor for treatment of cancer， IC50 for EGFR d746~750, EGFR L858R/T790, EGFR WT was in nanomolar level.；WO2017120429（Example 2）；陈婷婷要求上线，2023/9/15
References	[1]. Song Y.T, et al. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase. The United States, WO2017120429 A1. 2017-07-13.

Molecular Formula	C₂₈H₃₃N₇O₂
Molecular Weight	499.61

EGFR-IN-87

Use of EGFR-IN-87

Names

EGFR-IN-87 Biological Activity

Chemical & Physical Properties