SH-BC-893
Modify Date: 2024-01-02 17:41:15
SH-BC-893 structure
|
Common Name | SH-BC-893 | ||
|---|---|---|---|---|
| CAS Number | 1841409-92-4 | Molecular Weight | 325.921 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H32ClNO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SH-BC-893SH-BC-893 is a water-soluble, orally bioavailable synthetic sphingolipid that triggers nutrient transporter internalization and also blocks lysosome-dependent nutrient generation pathways in cancer cells, activates protein phosphatase 2A (PP2A), leading to mislocalization of the lipid kinase PIKfyve; selectively kills cells expressing an activated form of the anabolic oncogene Ras in vitro and in vivo. |
| Name | SH-BC-893 |
|---|
| Description | SH-BC-893 is a water-soluble, orally bioavailable synthetic sphingolipid that triggers nutrient transporter internalization and also blocks lysosome-dependent nutrient generation pathways in cancer cells, activates protein phosphatase 2A (PP2A), leading to mislocalization of the lipid kinase PIKfyve; selectively kills cells expressing an activated form of the anabolic oncogene Ras in vitro and in vivo. |
|---|---|
| References | References 1. Kim SM, et al. J Clin Invest. 2016 Nov 1;126(11):4088-4102. View Related Products by Target Other Targets |
| Molecular Formula | C19H32ClNO |
|---|---|
| Molecular Weight | 325.921 |