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  • DC Chemicals Limited
  • China
  • Product Name: SH-42
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

2143952-36-5

2143952-36-5 structure
2143952-36-5 structure
  • Name: SH-42
  • Chemical Name: SH-42
  • CAS Number: 2143952-36-5
  • Molecular Formula: C25H38O4
  • Molecular Weight: 402.57
  • Catalog: Research Areas Cancer
  • Create Date: 2022-05-24 19:20:18
  • Modify Date: 2024-01-13 13:48:14
  • SH-42 is a potent and selective inhibitor of human Δ24-dehydrocholesterol reductase (DHCR24), with an IC50 of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice[1].

Name SH-42
Description SH-42 is a potent and selective inhibitor of human Δ24-dehydrocholesterol reductase (DHCR24), with an IC50 of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice[1].
Related Catalog
Target

IC50: 42 nM (DHCR24)[1]

References

[1]. Müller C, et, al. New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase. Eur J Med Chem. 2017 Nov 10;140:305-320.

Molecular Formula C25H38O4
Molecular Weight 402.57