SH-42

Modify Date: 2024-01-13 13:48:14

SH-42 Structure
SH-42 structure
Common Name SH-42
CAS Number 2143952-36-5 Molecular Weight 402.57
Density N/A Boiling Point N/A
Molecular Formula C25H38O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SH-42


SH-42 is a potent and selective inhibitor of human Δ24-dehydrocholesterol reductase (DHCR24), with an IC50 of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice[1].

 Names

Name SH-42

 SH-42 Biological Activity

Description SH-42 is a potent and selective inhibitor of human Δ24-dehydrocholesterol reductase (DHCR24), with an IC50 of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice[1].
Related Catalog
Target

IC50: 42 nM (DHCR24)[1]

References

[1]. Müller C, et, al. New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase. Eur J Med Chem. 2017 Nov 10;140:305-320.

 Chemical & Physical Properties

Molecular Formula C25H38O4
Molecular Weight 402.57