m-PEG6-Amine

Modify Date: 2024-01-02 17:42:42

Use of m-PEG6-Amine

m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonym	More Synonyms

Description	m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.

Hazard Codes	Xi

m-PEG6-azide

CAS#:1043884-49-6

~61%

m-PEG6-Amine

CAS#:184357-46-8

Literature: Seguer, J.; Selve, C.; Allouch, M.; Infante, M. R. Journal of the American Oil Chemists' Society, 1996 , vol. 73, # 1 p. 79 - 86

2,5,8,11,14,17-...

CAS#:23601-40-3

m-PEG6-Amine

CAS#:184357-46-8

Literature: Journal of the American Oil Chemists' Society, , vol. 73, # 1 p. 79 - 86

m-PEG6-Tos

CAS#:155887-96-0

m-PEG6-Amine

CAS#:184357-46-8

Literature: Journal of the American Oil Chemists' Society, , vol. 73, # 1 p. 79 - 86

hexaethyleneglycol

CAS#:2615-15-8

m-PEG6-Amine

CAS#:184357-46-8

Literature: Journal of the American Chemical Society, , vol. 117, # 23 p. 6249 - 6253

Precursor 3
CAS#:1043884-49-6 m-PEG6-azide CAS#:23601-40-3 2,5,8,11,14,17-... CAS#:2615-15-8 hexaethyleneglycol
DownStream 0

3,6,9,12,15,18-HEXAOXANONADECAN-1-AMINE

1-amino-3,6,9,12,15,18-hexaoxanonadecane

methyletherhexaethyleneglycol amine