CL2A

Modify Date: 2024-01-21 14:19:31

CL2A structure	Common Name	CL2A
	CAS Number	1846605-04-6	Molecular Weight	1106.22
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₁H₇₉N₉O₁₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CL2A

CL2A is a complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].

Name	CL2A

Description	CL2A is a complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology
Target	Alkyl/ether
References	[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet

Molecular Formula	C₅₁H₇₉N₉O₁₈
Molecular Weight	1106.22

CL2A

Use of CL2A

Names

CL2A Biological Activity

Chemical & Physical Properties