TAS4464
Modify Date: 2024-01-24 21:36:47
TAS4464 structure
|
Common Name | TAS4464 | ||
|---|---|---|---|---|
| CAS Number | 1848959-10-3 | Molecular Weight | 506.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H23FN6O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TAS4464TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1]. |
| Name | TAS4464 |
|---|---|
| Synonym | More Synonyms |
| Description | TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50：0.955 nM (NAE)[1] |
| In Vitro | TAS4464 treatment inhibits cullin neddylation and subsequently induces the accumulation of CRL substrates such as CDT1, p27, and phosphorylates IκBα in 47 human cancer cell lines. |
| References |
| Molecular Formula | C21H23FN6O6S |
|---|---|
| Molecular Weight | 506.51 |
| MFCD32067967 |