Actein
Actein structure
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Common Name | Actein | ||
|---|---|---|---|---|
| CAS Number | 18642-44-9 | Molecular Weight | 676.834 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C37H56O11 | Melting Point | 246-250ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of ActeinActein is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in human bladder cancer. Actein has little toxicity in vivo[1][2]. |
| Name | Actein |
|---|---|
| Synonym | More Synonyms |
| Description | Actein is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in human bladder cancer. Actein has little toxicity in vivo[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Melting Point | 246-250ºC |
| Molecular Formula | C37H56O11 |
| Molecular Weight | 676.834 |
| Exact Mass | 676.382263 |
| PSA | 156.67000 |
| LogP | 5.67 |
| Index of Refraction | 1.610 |
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
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Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa.
J. Nat. Prod. 73(12) , 2024-8, (2010) Black cohosh (Actaea racemosa) is a frequently used herbal remedy for the treatment of mild climacteric symptoms. In the present study, the modulation of γ-aminobutryic acid (GABA)-induced chloride cu... |
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Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells.
Phytomedicine 15(6-7) , 504-11, (2008) The purpose of this report is to explore the growth inhibitory effect of extracts and compounds from black cohosh and related Cimicifuga species on human breast cancer cells and to determine the natur... |
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Studies on the Chinese crude drug "shoma." IX. Three novel cyclolanostanol xylosides, cimicifugosides H-1, H-2 and H-5, from cimicifuga rhizome.
Chem. Pharm. Bull. 43(5) , 771-6, (1995) Three new cyclolanostanol xylosides were isolated from a batch of commercial Cimicifuga Rhizome, cimicifugoside H-1 (1), C35H52O9, mp 260-262 degrees C, [alpha]D -43.5 degrees, cimicifugoside H-2 (2),... |
| β-D-Xylopyranoside, (1'R,2S,4'S,4aR,5'S,5aR,7R,7aR,7bR,8R,10R,11aS,12aS,12bS,14aR)-7-(acetyloxy)hexadecahydro-4'-hydroxy-1,1,5',7a,8,12a-hexamethylspiro[5H-cyclopropa[1',8'a]naphth[2',1':4,5]indeno [2,1-b]pyran-10(2H),2'-[3,6]dioxabicyclo[3.1.0]hexan]-2-yl |
| (1'R,2S,4'S,4aR,5'S,5aR,7R,7aR,7bR,8R,10R,11aS,12aS,12bS,14aR)-4'-Hydroxy-1,1,5',7a,8,12a-hexamethyl-2-(β-D-xylopyranosyloxy)hexadecahydro-2H-spiro[cyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b] pyran-10,2'-[3,6]dioxabicyclo[3.1.0]hexan]-7-yl acetate |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Actein
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- China
- Product Name: Actein
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- DC Chemicals Limited
- China
- Product Name: Actein
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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