SU 4984
Modify Date: 2024-01-10 07:48:18
SU 4984 structure
|
Common Name | SU 4984 | ||
|---|---|---|---|---|
| CAS Number | 186610-89-9 | Molecular Weight | 333.38400 | |
| Density | 1.34g/cm3 | Boiling Point | 649.1ºC at 760 mmHg | |
| Molecular Formula | C20H19N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 346.4ºC | |
Use of SU 4984SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer[1][2][3]. |
| Name | civentichem cv-409 |
|---|
| Description | SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
FGFR1:10-20 μM (IC50) |
| In Vitro | SU4984 (5-100 μM; 5 min) inhibits the kinase activity of FGFR1K with an IC50 of 10-20 μM in the presence of 1 mM adenosine triphosphate (ATP)[1]. SU4984 (10-90 μM; 5 min) inhibits the autophosphorylation of FGFR1 induced by aFGF in NIH 3T3 cells, with an IC50 of 20-40 μM[1]. SU4984 (5 μM) substantially reduces tyrosine phosphorylation of the wild-type receptor and reduces 50% phosphorylation of constitutive C2 KIT[2]. SU4984 (1-10 μM; 6 days) kills the C2 and P815 cells[2]. |
| References |
| Density | 1.34g/cm3 |
|---|---|
| Boiling Point | 649.1ºC at 760 mmHg |
| Molecular Formula | C20H19N3O2 |
| Molecular Weight | 333.38400 |
| Flash Point | 346.4ºC |
| Exact Mass | 333.14800 |
| PSA | 52.65000 |
| LogP | 3.23450 |
| Vapour Pressure | 9.81E-17mmHg at 25°C |
| Index of Refraction | 1.72 |
| Hazard Codes | Xi |
|---|