Hydroxytanshinone IIA

Modify Date: 2024-01-02 08:12:09

Hydroxytanshinone IIA Structure
Hydroxytanshinone IIA structure
Common Name Hydroxytanshinone IIA
CAS Number 18887-18-8 Molecular Weight 310.344
Density 1.3±0.1 g/cm3 Boiling Point 523.6±50.0 °C at 760 mmHg
Molecular Formula C19H18O4 Melting Point N/A
MSDS N/A Flash Point 270.4±30.1 °C

 Use of Hydroxytanshinone IIA


Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2[1].

 Names

Name 9-Hydroxy-1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
Synonym More Synonyms

 Hydroxytanshinone IIA Biological Activity

Description Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2[1].
Related Catalog
References

[1]. Peng Li, et al. Simultaneous determination of tanshinone IIA and its three hydroxylated metabolites by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2006;20(5):815-22.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 523.6±50.0 °C at 760 mmHg
Molecular Formula C19H18O4
Molecular Weight 310.344
Flash Point 270.4±30.1 °C
Exact Mass 310.120514
LogP 3.62
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.611

 Safety Information

Hazard Codes Xi

 Synonyms

9-Hydroxy-1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-9-hydroxy-1,6,6-trimethyl-
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