Danshenol B

Modify Date: 2024-01-09 15:03:08

Danshenol B Structure
Danshenol B structure
Common Name Danshenol B
CAS Number 189308-09-6 Molecular Weight 354.43900
Density 1.24±0.1 g/cm3 Boiling Point 501.3±50.0 °C at 760 mmHg
Molecular Formula C22H26O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Danshenol B


Danshenol B is a diterpenoid. Danshenol B has strong aldose reductase (AR) inhibitory activity with IC50 value of 0.042μM. Danshenol B can be used for the research of diabetic related complication resulted by metabolic abnormality, such as cataracts, retinopathy, neuropathy, and nephropathy[1].

 Names

Name (1R,10S)-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-11-one
Synonym More Synonyms

 Danshenol B Biological Activity

Description Danshenol B is a diterpenoid. Danshenol B has strong aldose reductase (AR) inhibitory activity with IC50 value of 0.042μM. Danshenol B can be used for the research of diabetic related complication resulted by metabolic abnormality, such as cataracts, retinopathy, neuropathy, and nephropathy[1].
Related Catalog
References

[1]. Tezuka Y, et al. Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge. Chem Pharm Bull (Tokyo). 1997 Aug;45(8):1306-11.  

 Chemical & Physical Properties

Density 1.24±0.1 g/cm3
Boiling Point 501.3±50.0 °C at 760 mmHg
Molecular Formula C22H26O4
Molecular Weight 354.43900
Exact Mass 354.18300
PSA 63.60000
LogP 3.42730
Vapour Pressure 7.19E-11mmHg at 25°C

 Synonyms

Phenanthro(1,2-b)furan-11(2H)-one,1,6,7,8,9,10-hexahydro-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-,(1R-trans)
Phenanthro(1,2-b)furan-11(2H)-one,1,6,7,8,9,10-hexahydro-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-,(1R,10S)
Danshenol B
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