Chlorothalonil

Modify Date: 2024-01-02 12:08:09

Chlorothalonil structure	Common Name	Chlorothalonil
	CAS Number	1897-45-6	Molecular Weight	265.911
	Density	1.7±0.1 g/cm3	Boiling Point	350.5±37.0 °C at 760 mmHg
	Molecular Formula	C₈Cl₄N₂	Melting Point	250-251ºC
	MSDS	Chinese USA	Flash Point	153.8±20.7 °C
	Symbol	GHS05, GHS06, GHS08, GHS09	Signal Word	Danger

Use of Chlorothalonil

Chlorothalonil is a broad spectrum fungicide and is effective in protecting plants against fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. Chlorothalonil is used for controlling of fungal foliar diseases of vegetables and crops[1][2].

Name	chlorothalonil
Synonym	More Synonyms

Description	Chlorothalonil is a broad spectrum fungicide and is effective in protecting plants against fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. Chlorothalonil is used for controlling of fungal foliar diseases of vegetables and crops[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Pengfei Zhang, et al. Low Dose Chlorothalonil Impairs Mouse Spermatogenesis Through the Intertwining of Estrogen Receptor Pathways With Histone and DNA Methylation.Chemosphere. 2019 Sep;230:384-395. [2]. Małgorzata Baćmaga, et al. The Influence of Chlorothalonil on the Activity of Soil Microorganisms and Enzymes. Ecotoxicology. 2018 Nov;27(9):1188-1202.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

References

[1]. Pengfei Zhang, et al. Low Dose Chlorothalonil Impairs Mouse Spermatogenesis Through the Intertwining of Estrogen Receptor Pathways With Histone and DNA Methylation.Chemosphere. 2019 Sep;230:384-395.

[2]. Małgorzata Baćmaga, et al. The Influence of Chlorothalonil on the Activity of Soil Microorganisms and Enzymes. Ecotoxicology. 2018 Nov;27(9):1188-1202.

Density	1.7±0.1 g/cm3
Boiling Point	350.5±37.0 °C at 760 mmHg
Melting Point	250-251ºC
Molecular Formula	C₈Cl₄N₂
Molecular Weight	265.911
Flash Point	153.8±20.7 °C
Exact Mass	263.881561
PSA	47.58000
LogP	2.88
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.633

Chlorothalonil MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NT2600000

CHEMICAL NAME :: Isophthalonitrile, tetrachloro-

CAS REGISTRY NUMBER :: 1897-45-6

LAST UPDATED :: 199710

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C8-Cl4-N2

MOLECULAR WEIGHT :: 265.90

WISWESSER LINE NOTATION :: NCR BG CG DG FG ECN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 310 mg/m3/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6750 mg/kg/90D-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - changes in bladder weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 142 gm/kg/80W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

MUTATION DATA

TEST SYSTEM :: Fish - not otherwise specified

DOSE/DURATION :: 1400 ppt/7D (Continuous)

REFERENCE :: HYHPDO Hunan Yixueyuan Xuebao. Journal of Hunan Medical College. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 12,153,1987 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,319,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,319,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1833 No. of Facilities: 3268 (estimated) No. of Industries: 21 No. of Occupations: 26 No. of Employees: 62724 (estimated) No. of Female Employees: 6716 (estimated)

Symbol	GHS05, GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H317-H318-H330-H335-H351-H410
Precautionary Statements	P260-P273-P280-P284-P304 + P340 + P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T+;N
Risk Phrases	R26;R37;R40;R41;R43;R50/53
Safety Phrases	S28-S36/37/39-S45-S60-S61-S36/37-S26
RIDADR	3276
RTECS	NT2600000
Packaging Group	I
Hazard Class	6.1(a)
HS Code	2926909090

Precursor 0
DownStream 8
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HS Code	2926909038
Summary	HS: 2926909038 fenoxanil Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:S(Registration certificate of import and export) Lowest tariff:6.5% General tariff:30.0%

Effects of seven antifouling compounds on photosynthesis and inorganic carbon use in sugar kelp Saccharina latissima (Linnaeus).

Arch. Environ. Contam. Toxicol. 63(3) , 365-77, (2012)

Macroalgae depend on carbon-concentrating mechanisms (CCMs) to maintain a high photosynthetic activity under conditions of low carbon dioxide (CO(2)) availability. Because such conditions are prevalen...

Development and validation of one-step ultrasound-assisted extraction for simultaneous determination of multiclass fungicides in soils.

J. AOAC Int. 98(1) , 192-200, (2015)

A rapid, efficient, and simple one-step ultrasound-assisted extraction (UAE) method was developed for the analysis of seven fungicides (cymoxanil, metalaxyl, mandipropamid, folpet, chlorothalonil, kre...

Photoreduction of chlorothalonil fungicide on plant leaf models.

Environ. Sci. Technol. 45(22) , 9582-9, (2011)

Photodegradation is seldom considered at the surface of vegetation after crop spraying. Chlorothalonil, a broad-spectrum foliar fungicide with a very widespread use worldwide, was considered. To repre...

meta-TCPN

2,4,5,6-Tetrachloroisophthalonitrile

Chloroalonil

MFCD00045594

2,4-Dicyanotetrachlorobenzene

1,3-dicyano-2,4,5,6-tetrachlorobenzene

2,4,5,6-tetrachlorobenzene-1,3-dicarbonitrile

2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile

m-Tcpn

2,4,5,6-tetrachloro-1,3-dicyanobenzene

Nopcocide

TPN

Perchloroisophthalonitrile

2,4,5,6-tetrachloroisophthalodinitrile

Chlorothalonil

EINECS 217-588-1

tetrachloroisophthalonitrile

Bravo

Daconil

1,3-Benzenedicarbonitrile, 2,4,5,6-tetrachloro-

Tetrachloroisophthalodinitrile

1,3-dicyanotetrachlorobenzene

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Chlorothalonil
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Chlorothalonil
Price: ￥178.0/1ml ￥178.0/1ml
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Chlorothalonil
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Chlorothalonil
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Chlorothalonil
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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