Oryzalin

Modify Date: 2024-01-03 02:27:05

Oryzalin Structure
Oryzalin structure
Common Name Oryzalin
CAS Number 19044-88-3 Molecular Weight 346.36000
Density 1.2 Boiling Point 514ºC at 760mmHg
Molecular Formula C12H18N4O6S Melting Point 141°C
MSDS Chinese USA Flash Point 264.6ºC

 Use of Oryzalin


Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle[1].

 Names

Name oryzalin
Synonym More Synonyms

 Oryzalin Biological Activity

Description Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle[1].
Related Catalog
References

[1]. Morejohn LC, et al. Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro. Planta. 1987 Oct;172(2):252-64.

 Chemical & Physical Properties

Density 1.2
Boiling Point 514ºC at 760mmHg
Melting Point 141°C
Molecular Formula C12H18N4O6S
Molecular Weight 346.36000
Flash Point 264.6ºC
Exact Mass 346.09500
PSA 163.42000
LogP 4.60430
Vapour Pressure 1.13E-10mmHg at 25°C
Index of Refraction 1.588

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WO9350000
CHEMICAL NAME :
Sulfanilamide, 3,5-dinitro-N(sup 4),N(sup 4)-dipropyl-
CAS REGISTRY NUMBER :
19044-88-3
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C12-H18-N4-O6-S
MOLECULAR WEIGHT :
346.40
WISWESSER LINE NOTATION :
ZSWR CNW ENW DN3&3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10000 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - gerbil
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
300 ug/plate
REFERENCE :
KHFKDF K'o Hsueh Fa Chan Yueh K'an. Progress in Sciences. (Kuo Chia K'o Hsueh Wei Yuan Hui, 2 Canton St., Taipei 107, Taiwan) V.1- 1973- Volume(issue)/page/year: 8,551,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Hazard Codes N:Dangerousfortheenvironment;
Risk Phrases R51/53
Safety Phrases S60
RIDADR UN 3077
RTECS WO9350000
HS Code 2935009017

 Customs

HS Code 2935009017
Summary 2935009017 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

 Articles26

More Articles
Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1.

Plant Cell 23(9) , 3412-27, (2011)

The dynamic instability of cortical microtubules (MTs) (i.e., their ability to rapidly alternate between phases of growth and shrinkage) plays an essential role in plant growth and development. In add...

Arabidopsis dynamin-related proteins, DRP2A and DRP2B, function coordinately in post-Golgi trafficking.

Biochem. Biophys. Res. Commun. 456(1) , 238-44, (2015)

Dynamin-related proteins (DRPs) are large GTPases involved in a wide range of cellular membrane remodeling processes. In Arabidopsis thaliana, two paralogous land plant-specific type DRPs, DRP2A and D...

Microtubules Are Essential for Guard-Cell Function in Vicia and Arabidopsis

Mol. Plant 5(3) , 601-10, (2012)

Radially arranged cortical microtubules are a prominent feature of guard cells. Guard cells expressing GFP-tubulin showed consistent changes in the appearance of microtubules when stomata opened or cl...

 Synonyms

4-(dipropylamino)-3,5-dinitrobenzene-1-sulfonamide
Surflan
Caswell No. 623A
4-(dipropylamino)-3,5-dinitrobenzenesulfonamide
Ryzelan
MFCD00078725
3,5-dinitro-N4,N4-dipropylsulfanilamide
Dirimal
ORYZALIN
3,5-Dinitro-4-dipropylamino-benzenesulphonamide
Dinitrodipropylsulfanilamide
Dirimal Extra
3,5-dinitro-N',N'-dipropylsulfanilamide
EINECS 242-777-0
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