TACE substrate (fluorogenic)

Modify Date: 2024-01-02 18:05:20

TACE substrate (fluorogenic) Structure
TACE substrate (fluorogenic) structure
Common Name TACE substrate (fluorogenic)
CAS Number 192723-42-5 Molecular Weight 1638.696
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C69H103N23O24 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TACE substrate (fluorogenic)


Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide. Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a fluorescence resonance energy transfer based substrate, the activity is measured by fluorescence intensity change upon cleavage[1].

 Names

Name 1-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-L-argininamide
Synonym More Synonyms

 TACE substrate (fluorogenic) Biological Activity

Description Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide. Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a fluorescence resonance energy transfer based substrate, the activity is measured by fluorescence intensity change upon cleavage[1].
Related Catalog
References

[1]. Yi Wang, et al. Protease assay method using site-specific fluorescence dye labeled protein as substrate. US9708638. 2017.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C69H103N23O24
Molecular Weight 1638.696
Exact Mass 1637.754639
LogP -2.78
Index of Refraction 1.683
Storage condition -15°C

 Synonyms

1-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-L-argininamide
L-Argininamide, 1-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-
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